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Contents

Oryx feature comparison chart

Feature

OryxNano

Oryx4

Oryx8

 
Vapor Diffusion Drops

Vapor Diffusion Multiple drops per reservoir single Protein

Vapor Diffusion Multiple drops per reservoir 2 Proteins

Vapor Diffusion Multiple drops per reservoir 3 Proteins

 

Vapor Diffusion Microseed Matrix Screening

Vapor Diffusion Additive Experiments

 

                                       Microbatch
with automatic oiling

 

Microbatch Additive experiments    

 

Microbatch Microseed Matrix Screening

 

 
Optimization

 

 

Quick-and-easy 2-D grid, 3 ingredients

 

 

Quick-and-easy 2-D grid, 4 ingredients  
7-D optimization grids
   

Central Composite, multi-variate experimental designs (7-channel)

 

 

 
Tools

Microlytic Crystal Forma filling

Fluidigm filling

 

   

The Major Differences between
Oryx8, Oryx4, and OryxNano

 

  • Oryx8 is the flagship Douglas Instruments protein crystallization robot.  It can set up sitting drop nanodrops down to 100 + 100 nl.  (For screening experiments the reservoirs must be predispensed by some other method such as a 12-channel pipette. For optimization experiments the reservoirs are filled automatically). Standard screening, additive and microseeding experiments are included as well as microbatch-under-oil screens (also down to 100 + 100 nl). Optimization experiments can be carried out  using up to 7 ingredients with full pH control, including multi-variate designs such as the Central Composite. In addition, quick-and-easy 2-D grid optimizations with up to 4 ingredients can be carried out in a few minutes. 

  • Oryx4 is the product for those users who do not want to do multi-variate optimization. As with the Oryx8, it performs standard screening, additive,  microseeding experiments and microbatch-under-oil screens (also down to 100+100 nl). Oryx4 can be upgraded to Oryx8 if multi-variate optimization becomes a requirement.

  • OryxNano is a compact option which has the capability of the Oryx4, except for microbatch and additive experiments. OryxNano can do quick-and-easy 2-D grid optimizations with up to 4 ingredients.

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