Douglas Instruments News
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March 2026 |
We are pleased to announce our latest publication in IUCrJ:
"Automated microbatch-under-oil phase diagrams to rationalize serial crystallography sample preparation"
Stubbs, J., Tremlett, C.J., Waitman, A., Harmer, N.J., Orville, A.M., Tews, I., Kolek, S. and Shaw Stewart, P.D., IUCrJ 13 (2026).
Open-access: https://doi.org/10.1107/S2052252526000448
Douglas Instruments has collaborated with the University of Southampton and Diamond Light Source to develop a fast and very simple method to generate phase diagrams of your proteins, which in practice often look very different from the “classical” phase diagrams that appear in textbooks.
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November 2024 |
Douglas Instruments has released a new experiment script for Automated Phase Diagram optimization. The new experiment provides a super-quick way to establish the phase diagram for your protein.
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May 2022 |
Douglas Instruments has published an article in collaboration with the National Physical Laboratory (NPL, Teddington, UK). The article discusses high-throughput approaches for measuring and analysing protein stability, including automated DLS screening approaches using Oryx robots.
Methods such as in-plate DLS enable rapid identification of conditions that promote protein stability and reduce aggregation while supporting improvement of sample quality, stability and reproducibility.
https://doi.org/10.3389/fmolb.2022.890862
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January 2020 |
The South Coast Biosciences (SoCoBio) Doctoral Training Partnership is offering a PhD student a unique opportunity to undertake research and training in structural biology and microfluidics.
The PhD will optimise nano-crystallisation to study two high value targets. Micro-seeding approaches are developed in collaboration with the highly innovative CASE partner Douglas Instruments [2]. Novel high-throughput approaches in nano-crystallisation using microfluidic platforms are developed at Southampton [3].
Primary supervisor:
Dr Ivo Tews, Biological Sciences, University of Southampton
Co-supervisors:
Dr S. Mark Roe, School of Life Sciences, University of Sussex
Dr Jonathan West, Medicine, University of Southampton
https://southcoastbiosciencesdtp.ac.uk/project/developing-novel-approaches-for-time-resolved-structural-biology/
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Douglas Instruments Ltd
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