Protein crystallization screening

▪ Minimal protein wasted (< 0.5 µL)

▪ Low consumable cost

▪ Only 10.0 µL required for a 96 well screen

Scaling-up

▪ Drop range from 100 nL to 8.0+ µL or larger

▪ Vary drop ratio or seed volume

▪ Dispense sitting drop, microbatch or hanging drop

Automatic Optimization

▪ Dispense concentration and pH gradients

▪ Multivariate experiment design

▪ Reservoir filling for optimization volumes up to 500 µL

Seed stock for rMMS

▪ Screen with highly concentrated seedstock

▪ Cross seeding from homologous proteins

▪ Dispense down to 10 nL seed stock