Douglas Instruments manufactures some of the most affordable and reliable liquid handling equipment designed for Protein Crystallization using the Vapor Diffusion and Microbatch methods.

We have been manufacturing products for Protein Crystallization since 1986. Although we became well known for the microbatch method our robots were always capable of setting up Vapor Diffusion drops. In the last two years we have refocused our design efforts on the Vapor Diffusion capability with the introduction of the Vapor Diffusion Upgrade with evaporation shield for Oryx4 and Oryx8 models as well as for the older Oryx6 model.

Our latest and most affordable robot designed purely for Vapor Diffusion is the OryxNano which includes the ability to do microseed matrix screening

We also offer a range of consumables for our robots. All of our machines are able to use our own and all other standard SBS type crystallization trays.